Ryan Reynolds and Jason Bateman star in The Change-Up. Growing up together, Mitch (Reynolds) and Dave (Bateman) were inseparable best friends, but as the years have passed they've slowly drifted apart.
Following a drunken night out together, Mitch and Dave's worlds are turned upside down when they wake up in each other's bodies and proceed to freak out.
Further complicating matters are Dave's sexy legal associate, Sabrina (Olivia Wilde), and Mitch's estranged father (Alan Arkin). With time not on their side, Mitch and Dave comically struggle to avoid completely destroying each other's lives before they can find a way to get their old ones back.